Background: Endotracheal tube cuff pressure (ETCP) management is a critical aspect of mechanical ventilation in intensive care units, and positional changes significantly affect pressure fluctuations. Aim: This letter reflects on our recently published study examining the effects of body position changes and vital signs on ETCP in children following Glenn shunt surgery and proposes a forward-looking roadmap for achieving optimal point-of-care (POC) management. Implications for Practice: We propose four paradigm-shifting directions: (1) transitioning from intermittent to continuous closed-loop control using IoT-enabled devices; (2) developing predictive algorithms using machine learning to forecast pressure changes before repositioning; (3) individualizing ETCP targets via bedside point-of-care ultrasound (POCUS) for anatomical profiling; and (4) integrating drug-position-pressure interactions into clinical decision-making. Conclusion: The future of ETCP management lies in anticipatory, automated, and individualized approaches. Multicenter trials comparing closed-loop, algorithm-driven systems against standard manual protocols are urgently needed.
Fazli, B., & Yaghubi, M. (2026). From Reactive Correction to Predictive Personalization: The Next Frontier in Endotracheal Tube Cuff Pressure Management at the Point of Care. (e28374). Evidence Based Care, (), e28374 https://doi.org/10.22038/ebcj.2026.97332.3282
MLA
Fazli, B., & Yaghubi, M. "From Reactive Correction to Predictive Personalization: The Next Frontier in Endotracheal Tube Cuff Pressure Management at the Point of Care" .e28374 , Evidence Based Care, , 2026, e28374. doi: 10.22038/ebcj.2026.97332.3282
HARVARD
Fazli B., Yaghubi M. (2026). 'From Reactive Correction to Predictive Personalization: The Next Frontier in Endotracheal Tube Cuff Pressure Management at the Point of Care', Evidence Based Care, (), e28374. doi: 10.22038/ebcj.2026.97332.3282
CHICAGO
B. Fazli & M. Yaghubi, "From Reactive Correction to Predictive Personalization: The Next Frontier in Endotracheal Tube Cuff Pressure Management at the Point of Care," Evidence Based Care, (2026): e28374, doi: 10.22038/ebcj.2026.97332.3282
VANCOUVER
Fazli B., Yaghubi M. From Reactive Correction to Predictive Personalization: The Next Frontier in Endotracheal Tube Cuff Pressure Management at the Point of Care. EBC. 2026;():e28374. doi: 10.22038/ebcj.2026.97332.3282
