Background Regular exercises decrease the risk of various diseases. This is a reason to recommend exercises for health promotion. Thus American Heart Association (AHA) and American College of Sport Medicine (ACSM) have issued guidelines for young people resistance exercises. Aim: To investigate the effect of resistance training exercise on hematological, immunological and coagulation parameters in sedentary young men. Methods: This quasi- experimental study was carried out on 26 healthy men (21.5±1.6 years old) who were selected at Bu-Ali Sina University and randomly assigned to control (n=13) and experimental (n=13) groups. The experimental group did AHA-ACSM exercise at 8 A.M. and control group continued their regular activities for 12 weeks. Fasting blood (5ml) was collected from antecubital vein before and 72 hours after exercise training. Hematological, immunological and coagulation parameters were measured by cell counting and ELISA methods. Data were analyzed by SPSS version 15 using t student and paired t-tests in order to compare groups before and after exercise training. Results: Twelve-weekresistance training exercise decreased Minimum Inhibitory Dilution (MID) and platelets significantly (P≤0.05). But it had no effect on MCV, MCH, MCHC, leukocytes, prothrombin time, clotting time and bleeding time. Conclusion: Results of the study showed that 12 -weeks AHA-ACSM exercise maintains hematological, immunological and coagulation parameters in physiological normal range in sedentary young men and resulted in optimal level of blood elements.
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