Comparison of the Effects of Relaxation and Vitamin B6 on Emotional and Physical Symptoms in Premenstrual Syndrome

Document Type: Original Quantitative and Qualitative Research Paper

Authors

1 BSc in Midwifery, School of nursing & midwifery, Rafsanjan University of Medical Science, Rafsanjan, Iran

2 Assistant Professor of Nursing, Department of Nursing, School of nursing & midwifery, Rafsanjan University Of Medical Science, Rafsanjan, Iran

3 Candidate of Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

4 Associate Professor of physiology, Department of physiology-pharmacology, Rafsanjan University of Medical Science, Rafsanjan, Iran

Abstract

Background: Premenstrual syndrome (PMS) is consisted of multiple psychological and emotional symptoms. This disorder possesses adverse effects on women’ economic, social, familial and professional issues, therefore various medical therapies have been suggested, thus all have own side effects.
Aim: To compare the effects of relaxation and vitamin B6 on emotional and physical symptoms of PMS.
Method: This is a randomized clinical trial study with pre- and post-test design. The study was conducted on 150 girls living in public dormitory whom were randomly divided into three groups. The relaxation group trained in two sessions and then one week before menstruation, the taught techniques were carried out on a daily basis. The second group received 80mg vitamin B6 tablets QD for one week before menstruation and then three times a week for one cycle. The third group received no intervention as control group. Each day, data were collected using a researcher-made questionnaire and where analyzed using SPSS version 14 with paired T and ANOVA tests.
Results: The mean age of the participants was 20.6±1.5 and their average weight was 54.1± 6.6. The mean scores of psychological symptoms after the interventionwere 1.2± 0.2 in vitamin B6 group, 0.3± 0.7 in relaxation group, and 1.6 ± 0.4 in the control group (p<0.001). Vitamin B6 and relaxation were both effective in reducing the psychological symptoms and this change was more prominent in the psychiatric symptoms in the relaxation group. The mean score of physical symptoms before the intervention, showed significant difference among the groups (p<0.01); and after the intervention it was 0.8±0.2 in vitamin B6, 1.6±0.3 in the relaxation group, and 1.0±0.5 in the control group (P<0.001). Paired t-test showed significant difference in the scores before and after the intervention, within the vitamin B6 group (p<0.001); just vitamin B6 was effective in reduction of the physical symptoms of PMS.
Conclusion: Relaxation and vitamin B6 both are effective in reducing the psychological symptoms of PMS; but vitamin B6 is more efficient in alleviating of the physical symptoms compared with relaxation.

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  1. Montazeri S. Comparison Effects of Vitamin B-6 and E on PMS Symptom in Students Living in Dormitories Shhydbhshty. Thesis of MS. 2001:5-10. (Persian)
  2. Palter S, Olive DL. Reproductive Physiology. Novak’s Gynecology (Berek JS, Adashi EY, Hillard PA, eds) Baltimore, MD): Williams & Wilkins. 1996:149-72.
  3. Berek, J., Berek & Novak Gynecology: Translate by Ghazijahani B, Zonuzi A, Bahrami N. Tehran, Iran: Golban publication, 2007: p. 471-501. (Persian)
  4. Hossein zare st. The Effect of Premenstrual Syndromes on The Function of Short-term, Long-term and Provident Memory of Afflicted Women. Iranian journal of obstetrics, gynecology and infertility. 2009;3(12):1-8. (Persian)
  5. Khajehei M, Abdali K, Parsanezhad Me, Tabatabaee Hr. Effect of Treatment with Dydrogesterone or Calcium Plus Vitamin D on The Severity of Premenstrual Syndrome. International Journal of Gynecology & Obstetrics. 2009;105(2):158-61.
  6. Braverman, P.k., Premenstrual Syndrome and Premenstrual Dysphoric Disorder. J Pediatr Adolesc Gynecol, 2007. 20(1): p. 3-12.
  7. Shahpoorian F, Mahmoodi Z, Hosseini F, Bastani F, Parsay S. Premenstrual Syndrome (PMS) and The Related Symptoms among Students of Iran University of Medical Sciences (IUMS). Iran Journal of Nursing. 2006;18(44):57-66. (Persian(
  8. Khalatbari J Ss. The Effect of Relaxation on Premenstrual Syndrome in Dormitory Students of Azad Tonekabon University of Iran. Procedia-Social and Behavioral Sciences 2013;8:1580–4.
  9. Biggs, W.s. and R.h. Demuth, Premenstrual Syndrome and Premenstrual Dysphoric Disorder. Am Fam Physician, 2011. 84(8): p. 918-24.
  10. Hariri FZMoghaddam-Banaem LSiah Bazi SSaki Malehi AMontazeri A. The Iranian version of the Premenstrual Symptoms Screening Tool (PSST): a validation study. Arch Womens Ment Health. 2013 Dec;16(6):531-7.
  11. Jurgens T, Whelan Am. Advising Patients on the Use of Natural Health Products to Treat Premenstrual Syndrome. Canadian Pharmacists Journal/Revue des Pharmaciens du Canada. 2009;142(5):228-33.
  12. Cunningham, F.g., et al., Obstetricia de Williams. 2013: McGraw Hill Brasil.
  13. Dehghan Manshadi, F., et al., The Effect of a Three–Month Regular Aerobic Exercise on Premenstrual Syndrome. Journal of Rafsenjan University of Medical Sciences, 2008. 7(2): p. 89-98.
  14. Dennehy, C.e., The Use of Herbs and Dietary Supplements in Gynecology: an Evidence Based Review. J Midwifery Womens Health, 2006. 51(6): p. 402-9.
  15. Abraham, G. and R. Rumley, Role of Nutrition in Managing the Premenstrual Tension Syndromes. J Reprod Med, 1987. 32(6): p. 405-22.
  16. Ebrahimi, E., et al., Effects of Magnesium and Vitamin B6 on the Severity of Premenstrual Syndrome Symptoms. J Caring Sci, 2012. 1(4): p. 183-9.
  17. Bastable, S.b., Nurse as Educator: Principles of Teaching and Learning for Nursing Practice. 2003: Jones & Bartlett Learning.
  18. Taylor, D., Perimenstrual Symptoms and Syndromes: Guidelines for Symptom Management and Self-care. Advanced Studies in Medicine, 2005. 5(5): p. 228-41.
  19. Dvivedi, J., et al., Effect of ‘61-points Relaxation Technique’on Stress Parameters in Premenstrual Syndrome. Indian j physiol pharmacol, 2008. 52(1): p. 69-76.
  20. LotfiKashani  F, S.K., Pashashryfy H, The Effect of Muscle Relaxation Training in Reducing the Symptoms of Premenstrual Syndrome. 2007. 2(5) p.114-20. (Persian(
  21. Dixhoorn Jv, W.A., Relaxation Therapy. Rehabilitation and Prevention in Ischaemic   Heart Disease. eur j cardiovasc prev rehabil, 2005. 3(12): p. 202-193.
  22. Babazadeh, R. and A. Keramat, Premenstrual Syndrome and Complementary Medicine in Iran: a Systematic Review. Feyz . 2011. 15(2): p. 174-87 . (Persian(
  23. Bendich, A., The Potential for Dietary Supplements to Reduce Premenstrual Syndrome (PMS) Symptoms. J Am Coll Nutr, 2000. 19(1): p. 3-12.
  24. Nayeri Nd, Mohammadi S, Arazi T. Examining the Level of Adherence of Therapeutic Regime by the Family Caregivers of Stroke Patients. Canadian Journal on Medicine. 2011;2:87-98.
  25. Freeman, E.w., R.j. Derubeis, and K. Rickels, Reliability and Validity of a Daily Diary for Premenstrual Syndrome. Psychiatry Research, 1996. 65(2): p. 9-106-7.
  26. Jacobson E. Yoy must relax. New York: McGraw. 1957.
  27. Wyatt, K.m., et al., Efficacy of Vitamin B-6 in The Treatment of Premenstrual Syndrome: Systematic Review. Bmj, 1999. 318(7195): p. 1375-81
  28. Birjandi S. Comparision the Effect of Hypericum Perforatum and Vitamin B6 in The Treatment of Premenstrual Syndrom. Zahedan Journal of Research in Medical Sciences. 2011;4(13):1-5.
  29. Kendal l, K.e., The Effects of Vitamin B6 Supplementation on Premenstrual Symptoms. Obstetrics & Gynecology, 1987. 70(2): p. 145-9.
  30. Goodale IL, D.A., Benson H, Alleviation of Premenstrual Syndrome Symptoms with The Relaxation Response. Obstetrics & Gynecology, 1990. 75(4): p. 649-55.
  31. Nikbakht M, A.a., Comparison of 8-week Aerobic Exercise and Vitamin B6 on Premenstrual Syndrome and Non-Athletic Female Martyr Chamran University Ahvazhrkt. Harkat journal, Summer 2009(28.( p. 57-68 (persian).
  32. Valiani M, samadi Z, shadman F. Comparison the Effects of Aerobic Exercise and Vitamin B6 in Severity of Symptoms of Premenstrual Syndrome in Non-Athlete Girls. Complementary Medicine journal. 2013. 3(3): p.552-62 (persian).