The Effect of endurance exercise training on hematological, Immunological and coagulation parameters in young sedentary men

Document Type : Original Quantitative and Qualitative Research Paper

Authors

1 Assistant professor Exercise Physiology, Department of exercise physiology, Bu-Ali Sina University, Hamedan, Iran

2 PhD Student of Exercise Physiology, Department of exercise physiology, Bu-Ali Sina University, Hamedan, Iran

Abstract

Background Regular exercises decrease the risk of various diseases. This is a reason to recommend exercises for health promotion. Thus American Heart Association (AHA) and American College of Sport Medicine (ACSM) have issued guidelines for young people resistance exercises.
Aim: To investigate the effect of resistance training exercise on hematological, immunological and coagulation parameters in sedentary young men.
Methods: This quasi- experimental study was carried out on 26 healthy men (21.5±1.6 years old) who were selected at Bu-Ali Sina University and randomly assigned to control (n=13) and experimental (n=13) groups. The experimental group did AHA-ACSM exercise at 8 A.M. and control group continued their regular activities for 12 weeks. Fasting blood (5ml) was collected from antecubital vein before and 72 hours after exercise training. Hematological, immunological and coagulation parameters were measured by cell counting and ELISA methods. Data were analyzed by SPSS version 15 using t student and paired t-tests in order to compare groups before and after exercise training.
Results: Twelve-weekresistance training exercise decreased Minimum Inhibitory Dilution (MID) and platelets significantly (P≤0.05). But it had no effect on MCV, MCH, MCHC, leukocytes, prothrombin time, clotting time and bleeding time.
Conclusion: Results of the study showed that 12 -weeks AHA-ACSM exercise maintains hematological, immunological and coagulation parameters in physiological normal range in sedentary young men and resulted in optimal level of blood elements.

Keywords

References

  1. Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, et al. Physical Activity and Public Health, A Recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA. 1995;273(5):402-7.
  2. Haskell WL, Lee IM, Pate RR, Powell KE, Blair SN, Franklin BA, et al. Physical Activity and Public Health: Updated Recommendation for Adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc. 2007; 29(8): 1423-34
  3. Zar A, Fatemeh A, Khosrow E, Friborz H and Davar A. Effect of 8 Weeks Endurance Training on Immune System. Journal of the Dow University of Health Sciences Karachi. 2012, 6 (2): 56-61.
  4. Shamoon Noushad , Sadaf Ahmed , Hiba Jafr i  and Sikandar Khan Sherwani. Effect of Exercise on Hematological Parameters: A Study on Trained Versus Un-Trained Male Subjects. Pak. j. life soc. Sci. 2012;10)1): 18-21.
  5. de Meirelles L. R., A. C. Mendes-Ribeiro, M. A. P. Chronic Exercise Reduces Platelet Activation in Hypertension. Scand J Med Sci Sports 2007;129(3):307-21.
  6. Gellish RL, Goslin BR, Olson RE, McDonald A, Russi GD, Moudgil VK. Longitudinal Modeling of the Relationship Between Age and Maximal Heart Rate. Med Sci Sports Exercise. 2007 ;39(5):822-9.
  7. Dill DB, Costill DL. Calculation of Percentage Changes in Volumes of Blood, Plasma, and Red Cells in Dehydration. J Appl Physiol. 1974;37(2):247-8.
  8. Fujitsuka S, Koike Y, Isozaki A, Nomura Y. Effect of 12 Weeks of Strenuous Physical Training on Hematological Changes. Mil Med. 2005 ;170(7):590-4.
  9. Schumacher YO, Grathwohl D, Barturen JM, Wollenweber M, Heinrich L, Schmid A, et al. Haemoglobin, Haematocrit and Red Blood Cell Indices in Elite Cyclists. Are the Control Values for Blood Testing Valid? Int J Sports Med. 2000;21(5):380-5.
  10.  Shirvani H,Masuodi Nezhad M. Effects of a Short Term Plyometric Training Program on Hemorrheological Parameters in Male College Basketball Players. Annals of Biological Research 2012; 3 (6):2813-2820
  11. Wu HJ, Chen KT, Shee BW, Chang HC, Huang YJ, Yang RS. Effects of 24 h Ultra-marathon on Biochemical and Hematological Parameters. World J Gastroenterol. 2004;10(18):2711-4.
  12. Pouramir M,Haghshenas O,Sorkhi H. Effects of Gymnastic Exercise on the Body Iron Status and Hematologic Profile.Iran J Med Sci 2004; 29(3):140-141.
  13. Sercan I, Hazar S, Demirci I.The Effect of Plyometric Training on Hematological Parametetrs in Alpine Skiers. Sport SPA ; 9(1): 15-19.
  14. Yükse S.Effect of Long-Term Training on Physical and Hematological Values in Young Female Handball Players. African Journal of  Microbiology  Research 2012; 6(5): 1018-1023.
  15. Ebrahim A.W and Abeer W.A. Efficiency of Exercise Program on CD 34+ Stem Cell, Blood Components and Some Physical and Skill. Journal of American Science 2012;8(11): 212-219.
  16. Bonsignore MR, Morici G, Santoro A, Pagano M, Cascio L, Bonanno A, et al. Circulating Hematopoietic Progenitor Cells in Runners. J Appl Physiol. 2002;9(3)1691-7.
  17. Kochańska-Dziurowicz A,Woźniak-Grygiel E, Bogacz A, Bijak A. The Effect of Maximal Physical Effort (the Refusal Test) on Erythrocytic System Parameters, Hemoproteins and Erythropoietin Concentrations in Blood of Junior Ice Hockey Team. Biology of Sport 2007; 24 (3):227-239.
  18. Van Craenenbroeck EM, Pelle AJ, Beckers PJ, Possemiers NM, Ramakers C, Vrints CJ, et al. Red Cell Distribution Width as a Marker of Impaired Exercise Tolerance in Patients with Chronic Heart Failure. Eur J Heart Fail. 2012;14(1):54-60.
  19.  Al-Bewyaney H.R Complete Blood Count in Athletic and Nonathletic Persons.Diyala journal for pure sciences 2011;7(1):74-81.
  20. Zech D, Rana S, Buchler MW, Zoller M. Tumor-Exosomes and Leukocyte Activation: an Ambivalent Crosstalk. Cell Commun Signal. 2012;10(1):37.
  21. Wardyn GG, Rennard SI, Brusnahan SK, McGuire TR, Carlson ML, Smith LM, et al. Effects of Exercise on Hematological Parameters, Circulating Side Population Cells, and Cytokines. Exp Hematol. 2008;36(2):216-23.
  22. Nehlsen-Cannarella SL, Nieman DC, Balk-Lamberton AJ, Markoff PA, Chritton DB, Gusewitch G, et al. The Effects of  Moderate Exercise Training on Immune Response. Med Sci Sports Exerc. 1991;23(1):64-70.
  23. Pedersen BK, Hoffman-Goetz L. Exercise and the Immune System: Regulation, Integration, and Adaptation. Physiol Rev. 2000;80(3):1055-81.
  24. Ghanbari N, mohammadi S.Effect 4 Weeks of Anaerobic RAST on Hematological Changes in Male Cake Boxers. Journal of  Applied exercise physiology 2008;5(10): 75-87. (persian).
  25. Yazdanpajooh S,Khosravi N, Nazarali P. The Effect of 8 Weeks of Selected Aerobic Training on Pulmonary Function and Hematological Factors in Chemical Weapon Female Victims Sport Physiology & Management Investigations 2012;8:63-71. (persian).
  26. Andrews JM. Determination of Minimum Inhibitory Concentrations. J Antimicrob Chemother. 2001;48 Suppl 1:5-16.
  27. Esmon CT. The Interactions Between Inflammation and Coagulation. Br J Haematol. 2005;131(4):417-30.
  28. Singh I, Quinn H, Mok M, Southgate RJ, Turner AH, Li D, et al. The Effect of Exercise and Training Status on Platelet Activation: do Cocoa Polyphenols Play a Role? Platelets. 2006;17(6):361-7.
  29. Mazzeo RS. Catecholamine Responses to Acute and Chronic Exercise. Med Sci Sports Exerc. 1991;23(7):839-45.
  30. Karpatkin S. Heterogeneity of Human Platelets: Metabolic and Kinetic Evidence Suggestive of Young and Old platelets. J Clin Invest. 1969;48(6):1073-82.
  31. Robson-Ansley P, Barwood M, Canavan J, Hack S, Eglin C, Davey S, et al. The Effect of Repeated Endurance Exercise on IL-6 and SIL-6R and their Relationship with Sensations of Fatigue at Rest. Cytokine. 2009;45(2):111-6.
  32. Aliyari F,Sina SH, Khatibi S.N, translator. Hematology Coagulation and Transfusion Medicine, 20th edition,2001.(persian).
  33. Carter JW, Ready AE, Singhroy S, Duta E, Gerrard JM. The Effect of Exercise on Bleeding Time and Local Production of Prostacyclin and Thromboxane. Eur J Appl Physiol Occup Physiol. 1989;59(5):355-9.
  34. Karakoc Y, Duzova H, Polat A, Emre MH, Arabaci I. Effects of Training Period on Haemorheological Variables in Regularly Trained Footballers. Br J Sports Med. 2005;39(2):e4.
  35. Meirelles L. R, Mendes-Ribeiro A. C, and etal. Chronic Exercise Reduces Platelet Activation in Hypertension:Upregulation of the L-Arginine-Nitric Oxide Pathway. Scand J Med Sci Sports 2007;1-8.
  36. El-Sayed MS, El-Sayed Ali Z, Ahmadizad S. Exercise and Training Effects on Blood Hemostasis in Health and Disease: an Update. Sports Med. 2004;34(3):181-200.
Evidence Based Care
Volume 3, Issue 1 - Serial Number 1
شماره پیاپی ششم
April 2013
Pages 37-48

Files

Share

How to cite

Statistics