Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701An Evidence Based Review on Oriental Medicine for the Treatment of Herpes Simplex Infections and Their Availability in Iranمروری بر شواهد درمانهای گیاهی طب شرقی برای تبخال و بررسی در دسترس بودن آنها در ایران716285610.22038/ebcj.2014.2856ENHoda AziziAssistant Professor of Complementary Medicine, Department of Chinese and Complementary Medicine, School of traditional and Complementary medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Addiction Research Center, Mashhad University of Medical Sciences, Mashhad, Iran0000-0003-1120-2217Abdollah BahramiAssociate professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranHamidreza Bahrami TaghanakiAssistant Professor of Complementary Medicine, Department of Chinese and Complementary Medicine, School of traditional and Complementary medicine, Mashhad University of Medical Sciences, Mashhad, Iran0000-0002-5756-0952Mohammad Hossein AyatiAssistant Professor of Traditional Medicine, Department of Traditional Medicine, School of Traditional Iranian Medicine, Tehran University of Medical Sciences, Tehran, IranHoma AziziPhD candidate in Crop Ecology, Department of Agronomy, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, IranHamideh AziziGynecology resident, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranSeyed Kazem FarahmandAssistant Professor of Complementary Medicine, Department of Chinese and Complementary Medicine, School of traditional and Complementary medicine, Mashhad University of Medical Sciences, Mashhad, IranMahmoud Mohammadzadeh ShabestariAssociate professor of Cardiology, Department of Cardiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranShapour BadieeAssistant Professor of Complementary Medicine, Department of Chinese and Complementary Medicine, School of traditional and Complementary medicine, Mashhad University of Medical Sciences, Mashhad, IranSeyed Reza Habibzadeh ShojaeiMedical student, Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranFarahnaz Khalighi-SigaroodiAssistant professor, Department of Pharmacognosy & Pharmaceutics, Institute of Medicinal Plants, ACECR, Karaj, IranJournal Article20130908Background: Herpes Simplex Virus (HSV) infections are very common in Iran and worldwide and the risk for resistance to anti-herpetic drugs has increased recently. Alternative antiherpetic agents seem necessary to control and reduce the emergence of -resistant strains. Oriental medicine suggests some herbal options for the treatment of herpes lesions. <br/>Aim: This study reviews some of the common herbal treatments in oriental medicine for herpes and their availability in Iran. <br/>Methods: In this narrative review, information on in vitro and in vivo studies and clinical trials was searched via international databases including PubMed and SCOPUS, using herpes, herb, Oriental medicine, Chinese medicine and the names of herbs as keywords, which resulted in 45 related articles; of these, 38 entered this review. The inclusion criteria were the in vitro and in vivo studies, randomized controlled trials and reviews with acceptable levels of evidence. Information regarding those herbs in traditional Iranian medicine, their availability in Iran, and the available pharmaceutical products in this country were investigated through Persian references. <br/>Results: Among herbs suggested by Oriental herbal medicine for the treatment of herpes lesions, Melia azedarach, Aloe barbadensis, Rheum palmatum, Salvia officinalis, Melissa officinalis, Melaleuca alternifolia, Hypericum perforatum, Crataegus pinnatifida, Punica granatum and Rheum palmatum, are backed by acceptable scientific evidence, and are available in Iran. <br/>Conclusion: Considering the evidence and availability of many of Oriental herbal medicines for herpes in Iran, they can be utilized for treatment and research purposes.Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701Effect of Touch on the Intensity and Duration of Venipuncture Pain in the School-age Childrenتأثیر لمس بر شدت و مدت درد ناشی از رگگیری در کودکان دبستانی1724285710.22038/ebcj.2014.2857ENAli SafariMS in Pediatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran0000-0002-3783-3538Hamidreza Behnam Vashaninstructor of Pediatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran0000-0002-9076-2900Tayebeh ReyhaniInstructor of Pediatric Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran0000-0003-1419-4902Alireza Ataei NakheiAssistant Professor of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranJournal Article20140121Background: Pain has physiological and psychological effects on a child's life and various body systems. Tactile stimulation affects the central nervous system and releases analgesic drugs resulting in the inhibition of pain. <br/>Aim: The main purpose of this study was effect of touch on the intensity and duration of pain during venipuncture in school-age children. <br/>Methods: This clinical trial was conducted on 60 children of school age in the emergency department of Imam Reza (AS) hospital and doctor Sheikh Hospital in 2014. Children were selected by convenience sampling and randomly divided into two groups, touch and control group. Touch group received intervention for 5 minutes by palms movements and kicks on the site before and during venipuncture by researcher, and then venipuncture was immediately performed by a nurse colleague. The control group did not receive any intervention. FACES instruments were used to assess pain intensity. Pain was measured for 5 min by a chronometer. Data were analyzed by Kolmogorov-Smirnov, Chi-square tests, Mann - Whitney and independent t-test using SPSS software version 11. <br/>Results: In this study, 65% were boys and 35% girls. The average age of children was 8.3±2.3 years. There was a significant difference between touch and control groups in pain of needle insertion into the skin within the first second (p<0.001). Independent t-tests showed that there was no significant difference between touch (242.0±67.7) and control (278.0±82.3) groups in duration of venipuncture pain (p=0.07). <br/>Conclusion: Touch is effective in reducing the intensity of pain during venipuncture in children. This is an easy and practical nursing intervention to reduce negative impact of pain on children.Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701Effect of Field massage on physiological jaundice in infants: a randomized Clinical trialتأثیر ماساژ فیلد بر زردی فیزیولوژیک نوزادان: یک مطالعه کارآزمایی بالینی تصادفیشده2534285810.22038/ebcj.2014.2858ENAlehe SeyyedrasooliInstructor of Nursing, Department of Medical-Surgical, school of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran0000-0002-2061-6991Leila ValizadeAssociate Professor of Pediatrics, school of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranMohammad Bager HosseiniAssociate Professor of Pediatrics, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranMohammad Asghari JafarabadiAssistant Professor of Road Traffic Injury Research Center, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, IranMasume MohammadzadMaster Student of Neonatal Intensive Care Nursing, school of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranJournal Article20140224Background: Jaundice is the most common cause of infant’s hospitalization. Infancy and especially the first few days after birth has important role on human mental and psychophysical Health in the future. <br/>Aim: To investigate the effects of massage on infants’ physiological jaundice. <br/>Methods: This single-blind clinical trial was performed at Tabriz Alzahra hospital. In this study, 47 healthy full-term infants, which their first day serum bilirubin was less than 5 mg/dl, were selected with accessibility sampling method. The participants were randomly assigned to case (n=22) and control (n=25) groups. The neonates in the case group were massaged by mother for 4 days from the first day of birth. The control group received routine care only. The main variables of study included skin bilirubin level, number of defecations and time of passage of first meconium. Data analysis was applied by SPSS 13 using chi square, Mann-whitney U and Independent t-test. <br/>Results: Within four days of study, there was no statistically significant differences between the two groups in terms of skin bilirubin and number of defecations (p>0.05). The mean time (95% CI= - 7.53, - 0.10) of passage of the first meconium in case group was less than that in the control group which was statistically significant (P= 0.044). <br/>Conclusion: The results show that neonates massage within four days has no effect on skin bilirubin level but it will affect on the incidence of physiologic jaundice by diminishing the time of passage of the first meconium.Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701The Effect of Vanilla Odor on Response to Venipuncture Pain in Preterm Newborns: a Randomized Control Clinical Trialتأثیر بوی وانیل بر پاسخ به درد ناشی از خونگیری وریدی در نوزادان نارس: کارآزمایی بالینی شاهددار تصادفی3542286110.22038/ebcj.2014.2861ENMahnaz JebreiliInstructor of Nursing, Department of Pediatrics, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranElaheh SeyedrasooliInstructor of Nursing, Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran0000-0002-2061-6991Morteza GhojazadehAssociate Professor of Physiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranMohammadbagher HosseiniAssociate professor of Neonatology, Department of Pediatrics, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranHamed HamishehkarAssistant Professor of Pharmacology, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, IranHanie Neshat EsfahlaniMS in Nursing, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranJournal Article20140212Background: Studies have shown that use of olfactory stimuli during painful medical procedures reduces infants’ response to pain. <br/>Aim: The main purpose of this study was investigating the effect of vanilla on pain response in preterm infants during and after venipuncture. <br/>Methods: This study is a randomized clinical trial. Ninety preterm infants, who were randomly selected and divided into two groups of control and vanilla odor, were classified into 45 people. Infants in the vanilla group were exposed to vanilla odor from 5 minutes before and up to 30 seconds after sampling, and infants of control group were exposed to smell of distilled water. The pain score was measured using premature infant pain profile (PIPP) score 30 seconds prior, during and 30 seconds after sampling. Statistical analyses were done using SPSS 16 software. Analyses were done by t-test, chi-square and repeated measure analyses. <br/>Results: Despite the differences between the pain scores of two groups during and after sampling, statistical analyses showed no significant differences between them (p=0.36). <br/>Conclusion: Results of the present study showed that use of vanilla odor has no significant effect on premature infants’ pain during blood sampling.Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701Comparison of the effect of pressure support ventilation and volume assured pressure support ventilation on weaning patients off mechanical ventilation after cardiac surgeryمقایسه تأثیر تهویه حمایت فشاری و تهویه حمایت فشاری با حجم مطمئن بر جداسازی از تهویه مکانیکی در بیماران بعد از عمل جراحی قلب4352286310.22038/ebcj.2014.2863ENFarzaneh HasanzadehInstructor of Nursing, Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran0000-0003-0076-5129Zohreh Mohamadzadeh TabriziMS in critical care Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, IranShahram AminiAssociate professor of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran0000-0002-2785-1812Javad MalekzadehInstructor of Nursing, Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran0000-0002-4987-4740Seyedreza MazlomPhd candidate in Nursing, Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran0000-0001-6722-8411Journal Article20140220Background: Weaning from mechanical ventilation in the intensive care unit is an important step in the treatment process. More patients in less than 6 hours after cardiac surgery can be separated from mechanical ventilation and extubated. However, 20-40% of patients after cardiac surgery, due to dysfunctional ventilator weaning response (DVWR), still remain under mechanical ventilation. Therefore, a new method of mechanical ventilation such as volume assured pressure support ventilation (VAPSV) is needed in order to reduce the time of weaning from mechanical ventilation. <br/>Aim: To compare the effect of pressure support ventilation (PSV) with volume assured pressure support ventilation (VAPS) on time of weaning from mechanical ventilation in patients after cardiac surgery. <br/>Methods: This clinical trial study was conducted with the participation of 76 patients undergoing cardiac surgery in Imam Reza hospital of Mashhad, in 2013. Patients were randomly divided into two groups of pressure support ventilation (control) and pressure support ventilation with reliable volume (intervention) groups and the duration of mechanical ventilation and reintubation in both groups was recorded. The data were analyzed by SPSS software version 16 using t-student test and Mann-Whitney tests. <br/>Results: The mean duration of mechanical ventilation in VAPS group (65.7±5.8) significantly decreased compared with PSV (87.1± 5.8) (P = 0.015). <br/>Conclusion: Results of our study showed that VAPS method could reduce the time of weaning from mechanical ventilation and due to fewer complications; it can be used as an alternative method for weaning off mechanical ventilation.Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701Evaluating the Effect of Religious-Based Sex Education on Sexual Function of Married Womenبررسی تأثیر آموزشهای جنسی مبتنی بر آموزههای دینی بر عملکرد جنسی زنان متأهل5362291410.22038/ebcj.2014.2914ENFatemeh NameniMsc student of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad ,IranSedygheh YousefzadehInstructor of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad ,IranNahid GolmakaniInstructor of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad ,Iran0000-0002-2018-9774Mona Najaf NajafiAssociate in Biostatistics, School of medical science, Mashhad University of Medical Sciences, Mashhad, IranMehdi EbrahimiAssociate professor, Department of Islamic Studies, Mashhad University of Medical Sciences.Morteza Modares GharaviAssistant professor of clinical psychology, Research center of psychiatry and behavioral science, Mashhad University of Medical Sciences, Mashhad ,IranJournal Article20130917Background: Spirituality forms major parts of human life. Sexual need is one of the natural instincts and it is in dimension of spiritual needs, and neglecting it causes family and social problems. Sexual education is weak in our country and must be conform to religious beliefs. <br/>Aim: Determining the effect of religious-based sex education on sexual function of married women <br/>Methods: This single-group, semi-experimentalresearch was performed in 1391.Two health centers were randomly chosen among health centers of Mashhad. Thirty referred women were selected based on inclusion and exclusion criteria. They took part in sex education classes combining religious education for 6 weeks. Data was gathered by personal characteristic form and Female Sexual Function Index (FSFI) questionnaire. Data was analyzed by SPSS 11.5 software using statistic descriptive, paired T-test and linear regression. <br/>Results: The mean age of participants was 33.9±7.2, and 90% of them had secondary school education, and 83.3% were housewives. The total score of Female Sexual Function Index (FSFI) increased from 25.86±5.25 to 27.29±5 and there was significant statistical difference in sexual desire (p=0.007) and sexual satisfaction (p=0.01). <br/>Conclusion: religious-based sex education to married women can improve sexual function, components of sexual satisfaction and sexual desire.Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosisتأثیر برنامه تمرین در آب بر اینترلوکین-6 و اینترلوکین-10 بیماران مبتلا به مولتیپلاسکلروزیس6372291210.22038/ebcj.2014.2912ENNahid BezhehAssociate Professor of Exercise Physiology, Ferdowsi University of Mashhad, Faculty of Physical Education and Sports Science, Mashhad, IranMahmod SoltaniFaculty Member of Islamic Azad University of Mashhad, Department of Physical Education and Sports Science, Mashhad, IranHoma KhaleghzadeMaster of Exercise Physiology, hakim Sabzevari University of sabzevar, IranJournal Article20140111Background: Multiple Sclerosis is the most prevalent disease of the central nerve system. This disease affects different aspects of patient’s life. Multiple Sclerosis has negative effects on physical and mental health. Cytokines play an important role in the pathogenesis of Multiple Sclerosis and are major targets of therapeutic interventions. <br/>Aim: To investigate the effects of aquatic aerobic exercise on IL-6 and IL-10 in men with Multiple Sclerosis. <br/>Methods: In this randomized clinical trial, 30 patients with MS were randomly divided into two control and experimental groups. For experimental group, exercise program was applied for 8 weeks, 3 sessions per week with intensity of 50-60% of maximum heartbeat. IL-6 and IL-10 were analyzed before and after exercises. Analyzing data was done by SPSS ver. 18, and 0.05 significant level of independent T examination<sub>.</sub> <br/>Results: Results indicated that there was significant difference between the two groups in IL-6 (P<0/001) and IL-10 (P<0/004). <br/>Conclusion: aerobic training in watercan regulate the inflammatory and anti-inflammatory cytokines, and adjust IL-6 and IL-10 indexes. Experts can use these exercises as complementary treatment along with medical cure for MS patients.Mashhad University of Medical SciencesEvidence Based Care2008-24874220140701The Effectiveness of Sexual Education Focused on Cognitive Schemas, on the Improvement of Sexual Functioning among Female Married Studentsاثربخشی آموزش مهارتهای جنسی متمرکز بر طرحوارههای شناختی بر بهبود کنشوری جنسی دانشجویان متأهل زن7382292110.22038/ebcj.2014.2921ENParisa ZiaeeMA in Clinical Psychology, Department of Psychology, School of Educational Science and Psychology, Ferdowsi University of Mashhad, Mashhad, IranZohreh Sepehri ShamlouAssistant professor of Psychology, School of Educational Science and Psychology, Ferdowsi University of Mashhad, Mashhad, IranAli MashhadiAssistant professor of Psychology, School of Educational Science and Psychology, Ferdowsi University of Mashhad, Mashhad, IranJournal Article20131118Background: Sexual relationship plays a decisive role in human’s health and it seems that sexual education can enhance the quality of sexual relationship. <br/>Aim: Investigating the effectiveness of sexual education focused on cognitive schemas, on the improvement of sexual functioning of female married students. <br/>Methods: This research was carried out semi-experimentally and a pretest-posttest designed control group was used. A total of 28 persons were selected and put into two groups. Sexual education was offered to the experimental group for eight 90-minute sessions. In both groups, the degree of sexual functioning was measured and registered before and after intervention using women’s sexual functioning index questionnaire (FSFI), and was analyzed with SPSS version 16 and t-test<sub>.</sub> <br/>Results: T-test results showed significant relationship between the two groups in the overall scores of sexual functioning, sexual desire components, psychological arousal, moisture, orgasm and sexual satisfaction, in a way that in all cases the scores of the experimental group were significantly higher than those of the control group (p<0.001). However, t-test reported no significant difference between the two groups in terms of sexual pain component <br/>Conclusion: The present research demonstrated that sex education with focuse on cognitive schemas was an effective method for improving sexual functioning, and therefore, it is proposed that this matter should be taken into consideration by clinical therapists for enhancing the quality of couples’ relationships.